一本道

Photo of Anita 脰st

Anita Öst

Professor, Head of Division

Our research explores how molecular information carried by sperm shapes embryonic development and lifelong health. We aim to uncover the molecular mechanisms linking reproduction with metabolic disease.

From environment to embryo

Our research investigates how environmental factors, including diet and metabolic health, shape the molecular composition of sperm and influence fertilization, embryo development and offspring health. By combining experimental models with human studies, we aim to understand how sperm RNA and other molecular mechanisms regulate male fertility, developmental programming and lifelong health. This knowledge may ultimately improve reproductive health while providing new insights into the origins of metabolic disease.

News

Research

Video about the research 

From Fruit Flies to Human Health

Can a father's lifestyle influence the next generation? This video presents our discovery that diet before conception can alter offspring metabolism, using fruit flies to uncover molecular mechanisms that are conserved across species and relevant to human health.

一本道

Metabolism - a plainsplain Youtube channel

These video clips are produced for teaching at the Medical programme at the Faculty of medicine and health sciences at Link枚ping university.

Full publication list

2026

Anna Asratian, Signe Isacson, Unn 脰rtegren Kugelberg, Colum Walsh, Anita 脰st (2026) Cellular and Molecular Life Sciences (CMLS), Vol. 83, Article 243 (Article in journal)
Chien Huang, Joo-Hyun Park, Ali Altintas, Natasa Stanic, Kristine Kyle de Leon, Signe Isacson, Panagiotis Kalogeropoulos, Hande Topel, Tobias Madsen, Sebastian Zanner, Phillip M. M. Ruppert, Rocio Valdebenito, Jesper Havelund, Bjork Ditlev Marcher Larsen, Yen-Ting Chien, Wen-Chi Huang, Yovita Permata Budi, Yi-Fan Jiang, Andrea Livia Rocha, Niedson Correia Lima-Junior, Karolina Szczepanowska, Jan-Wilm Lackmann, Aleksandra Trifunovic, Eva Kildall Hejbol, Sonke Detlefsen, Ida Engberg Jepsen, Stefanie Hansborg Kolstrup, Ricardo Laguna-Barraza, Javier Martin-Gonzalez, Konstantin Khodosevich, Nils J. Faergeman, Marcelo A. Mori, Marc R. Friedlander, Anita 脰st, Romain Barres, Jan-Wilhelm Kornfeld (2026) Nature Communications, Vol. 17, Article 3125 (Article in journal)

2025

Signe Isacson, Kajsa Karlsson, Stefan Zalavary, Anna Asratian, Unn 脰rtegren Kugelberg, Susanne Liffner, Anita 脰st (2025) Nature Communications, Vol. 16, Article 6571 (Article in journal)
Shamila Darvish Alipoor Astaneh, Parisa Norouzitallab, Anita 脰st, Maria Lerm (2025) Journal of Internal Medicine, Vol. 298, p. 16-30 (Article in journal)
Josefine Jonsson, Alexander Perfilyev, Unn 脰rtegren Kugelberg, Signe Skog, Axel Lindstrom, Sabrina Ruhrmann, Jones K. Ofori, Karl Bacos, Tina Ronn, Anita 脰st, Charlotte Ling (2025) Epigenomics, Vol. 17, p. 89-104 (Article in journal)

2024

Anita 脰st (2024) Antioxidants and Redox Signaling, Vol. 41, p. 429-429 (Article in journal)

Coworkers

Organisation